EMDA


Physion EMDA
Electro Motive Drug Administration




(Only available in UK)

A controllable method for delivery of drugs into the bladder wall and prostatic urethra has been developed.
Conventional administration of drugs for urologic pathologies is either by the systemic route or via intravesical instillation and subsequent passive diffusion into the urothelium. The well documented concerns with systemic administration are the small quantities of drug locating at the site of disease; and side effects which are occasionally severe. The problems associated with conventional intravesical instillation are the slow rate of diffusion across the tightly knit urothelium and a fundamental inability to control the rate of drug administration.

Now, a controllable method for delivery of drugs into the bladder wall and prostatic urethra has been developed by Physion. It comprises a non-invasive, painless local drug administration which provides greater clinical efficacy than does passive diffusion yet without the side effects seen with systemic administration.

Concept

EMDA utilizes an electrical current to impart an accelerated, directional (towards the tissues) movement of ionized drugs in an intravesical solution, which results in greater quantities of drugs being delivered to greater tissue depths than is achievable by passive diffusion. Furthermore, the rate of drug administration is fully controllable simply by varying the intensity of the electric current.

Key features & indications for use
  • Non-Invasive Technology
  • Uses Electricity to transport ionized and non-ionized water soluble drugs into body tissues
  • Facilitates high localized drug concentrations and minimal-absent systemic side effects
  • Local anaesthesia of the bladder
  • Intravesical treatment of IC Patients
  • Intravesical treatment of bladder cancer
  • Intravesical treatment of recurrent, infective cystitis
  • Intravesical treatment of hyperreflexic bladders
  • Intraprostatic treatment of non-specific prostatitis
  • Intraprostatic treatment of infective prostatitis
  • Transdermal treatment of Peyronie's Disease
Uses Electricity to transport ionized and non-ionized water soluble drugs into body tissues

Transdermal treatment of Peyronie's Disease